Precision Fluid Control for Advanced Therapy Manufacturing
Cell and gene therapy processes require precise control of fluid movement while protecting sensitive biological materials throughout development and manufacturing. Whether supporting process development, pilot production, or commercial manufacturing, fluid control components must deliver repeatable performance while maintaining the integrity of the fluid path.
Resolution Air proportional pinch valves provide high-resolution flow control without exposing the process fluid to internal valve components, making them well suited for applications where sterility, precision, and automation are critical.
Engineering Challenges in Cell & Gene Therapy
Cell and gene therapy workflows place unique demands on fluid handling systems. Engineers are often balancing process performance, sterility, and automation while working with valuable materials and tightly controlled operating conditions.
Common considerations include:
- Maintaining a sterile fluid path throughout the process
- Delivering precise and repeatable flow control
- Protecting sensitive biological materials
- Integrating fluid control into automated equipment
- Supporting consistent performance from process development through manufacturing
Reliable fluid handling helps reduce variability and supports consistent process performance throughout the product lifecycle.
Why Proportional Pinch Valves Are Used
Proportional pinch valves regulate flow by applying controlled compression to flexible tubing, allowing the process fluid to remain completely isolated from the valve mechanism.
For cell and gene therapy applications, this approach provides several advantages:
- Complete isolation of the process fluid
- High-resolution proportional flow control
- Reduced contamination risk
- Precise metering of process fluids
- Easy integration into automated fluid handling systems
Typical Cell & Gene Therapy Applications
- Process development
- Cell culture media handling
- Buffer preparation
- Reagent delivery
- Process fluid transfer
- Automated bioprocess equipment
- Pilot-scale manufacturing
Industries Using Cell & Gene Therapy Systems
- Bioprocessing
- Biotechnology
- Pharmaceutical Manufacturing
- Contract Development and Manufacturing Organizations (CDMOs)
Recommended Valve Solutions
The appropriate valve configuration depends on flow requirements, tubing size, control resolution, and system design.
H Series
Designed for applications requiring larger tubing sizes, increased pinch force, or higher flow rates.
DRV-1 Driver
Provides precise proportional valve control and seamless integration into automated process equipment.
Continue Your Research
Access technical documentation and educational resources to support valve evaluation and system design.
Designed for Critical Fluid Control Applications
Resolution Air develops proportional pinch valves for applications where precision, repeatability, and fluid integrity are essential.
Engineers choose Resolution Air because we provide:
- Patented proportional pinch valve technology
- High-resolution proportional flow control
- Robust valve designs for demanding bioprocess applications
- Responsive engineering support throughout evaluation, testing, and implementation
Ready to Discuss Your Application?
Every cell and gene therapy process has unique fluid handling requirements. Whether you’re developing a new process or scaling an existing system, our engineering team can help identify the appropriate proportional pinch valve for your application.
